Hosting 725 files, 2937 images, and 4 contributors.

Random Case

Pulmonary TB
Heather Borders, MD
over 8 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Case History

Teenager with seizure.

Case Detail

Anatomy: Brain-Spine
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 6 years ago
Updated: over 6 years ago
Tags: PEDS
Modality/Study Types: MR
Adobe32 PDF Imagej32 ImageJA

Case Images

Academic Case Revealer (Click to Expand)

Reveal Findings

MR – Axial T1, T2 and post-gadolinium T1 images of the brain show multifocal enhancing lesions with marked mass effect and edema.

Reveal Discussion

Burkitt’s lymphoma is a malignant non-Hodgkin’s lymphoma consisting of undifferentiated, B-cells. Three types are described: an endemic form typically found in Africa that typically affects the facial bones; a sporadic form that typically affects the abdominal viscera; and a HIV-associated form. Ebstein-Barr virus has a high association with this disease. Translocation at the c-MYC gene at chromosome 8q24 to the heavy chain on 14q32, or, less commonly, to the light chain at 2q11 is the underlying genetic defect. Primary central nervous system Burkitt’s lymphoma is extremely rare, being described by a few cases reports in the literature. The typical MRI appearance of CNS lymphoma is a poorly defined mass which is isointense on T1WI, hyperintense on T2WI, and diffusely enhancing (ring-enhancement is rare). On spectrospcopy, CNS lymphoma has very high lipid and choline peaks relative to creatinine ratios compared to astrocytomas.

Reveal Diagnosis

CNS Burkitts Lymphoma

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare