Hosting 723 files, 2931 images, and 4 contributors.

Random Case

Mediastinal Bronchogenic Cyst
Joseph Junewick, MD FACR
over 6 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Case History

Teenager with “cherubism”.

Case Detail

Anatomy: Neck-Face
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Benign
Created: over 7 years ago
Updated: over 7 years ago
Tags: PEDS
Modality/Study Types: CT
Adobe32 PDF Imagej32 ImageJA

Case Images

Academic Case Revealer (Click to Expand)

Reveal Findings

CT – Axial and coronal images show marked expansion of the mandible by multi-septated lytic lesions. Bone survey shows polyostotic involvement.

Reveal Discussion

Giant cell reparative granuloma is an uncommon lesion that is a reactive process and not a neoplasm. At histologic analysis, giant cell reparative granulomas demonstrate plump, bland fibroblasts and multinucleated giant cells surrounding foci of hemorrhage; osteoid production along hemorrhagic foci is commonly seen. The histologic appearance of GCRG is similar to that of brown tumor of hyperparathyroidism. GCRG occurs in patients in the 2nd and 3rd decades of life and has a predilection for the mandible and maxilla. Jaw lesions affect women more frequently than men (2:1 ratio). Patients present with pain and swelling; hormonal stimulation of pregnancy may lead to significant enlargement.

Reveal Diagnosis

Giant Cell Reparative Granuloma of the Mandible

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare