Hosting 728 files, 2951 images, and 4 contributors.

Random Case

Parathyroid Adenoma
Joseph Junewick, MD FACR
over 10 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Craniofacial Dysraphism

Case Detail

Anatomy: Neck-Face
Joseph Junewick, MD FACR
Diagnostic Category:
Created: over 11 years ago
Updated: over 10 years ago
Tags: PEDS
Modality/Study Types: CT 3D MR
Adobe32 PDF Imagej32 ImageJA


Newborn male with midface anomalies.

Case Images


Nasofrontal dysplasia with intracranial lipoma.

Clinical Notes

Hypertelorism, wideset and notched nares, narrow palpebral fissures and soft tissue prominence in the glabellar region.


CT – Axial with 3D volume rendered reformats demonstrate extensive midline craniofacial disorganization with osseous deficiency involving the maxilla, nasal bones, cribiform plates and frontal bones and confirms clinical deformities of hypertelorism and primitive proboscis.

MR – Midline subfrontal lipoma with no overt midline malformation (normal pituitary gland and intact corpus callosum and septum pellucidum) or cerebral dysgenesis.


Development of the midface (upper lip to forehead) occurs between the 4th and 8th post-ovulation week but the embryogenesis of craniofacial syndromes is poorly understood. Occurence of craniofacial syndromes is sporadic. Concurrent malformations of the brain are relatively common and largely determine longterm outcome. Several named craniofacial syndromes exist including Apert, Crouzon, Pfeiffer, Treacher-Collins, Roberts, Coffin-Lowry, Saethre-Chotzen, Noack, Jackson-Weiss, Carpenter, and Lowry.


Lowe LH, Booth TN, Joglar JM, Rollins NK. Midface anomalies in Children. Radiographics 2000; 20:907-922.

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare