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C7 Burst Fracture
Joseph Junewick, MD FACR
over 11 years ago
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Hypoxic-Ischemic Injury

Case Detail

Anatomy: Brain-Spine
Joseph Junewick, MD FACR
Diagnostic Category: Vascular
Created: over 7 years ago
Updated: over 4 years ago
Tags: PEDS
Modality/Study Types: CT
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Accidental asphyxiation in toddler.

Case Images


Hypoxic-Ischemic Injury


CT – Axial and coronal images show symmetric lentifirm nuclei hypodensity


Differential considerations for symmetric lentiform hypodensity include:
1) Toxic exposure (carbon monoxide, cyanide, methanol)
2) Nitrous waste accumulation (liver disease, portal hypertension, portosystemic shunts)
3) Non-ketotic hyperglycemia
4) Hypoglycemia
5) Hypoxic-ischemic disease
6) Metabolic disease (Leigh disease, Wilson disease, Hallervorden-Spatz disease)
7) Osmotic myelinolysis
8) Internal cerebral vein thrombosis
9) Encephalitis (Immune, viral)
10) Neoplasms (primary CNS lymphoma, glioma)


Hedge AN, Mohan S, Lath N, et al. Differential Diagnosis for Bilateral Abnormalities of the Basal Ganglia and Thalamus. Radiographic (2011); 31(1):5-30.

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