Hosting 721 files, 2924 images, and 4 contributors.

Random Case

Eosinophilic Granuloma
Joseph Junewick, MD FACR
over 8 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Metastatic Neuroblastoma

Case Detail

Anatomy: Genitourinary
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 9 years ago
Updated: over 6 years ago
Tags: PEDS
Modality/Study Types: CT
Adobe32 PDF Imagej32 ImageJA

Case Images


Metastatic Neuroblastoma; liver, retroperitoneal lymph nodes, skin and skeletal muscle


Large retroperitoneal mass displacing the aorta and inferior vena cava with numerous hepatic and enhancing subcutaneous and intramuscular lesions.


Skeletal muscle metastases are unusual but have been reported with lymphoma, Wilms tumor and clear cell sarcoma.

Neuroblastoma metastasis occurs by lymphatic or hematogenous routes. Regional lymph node metastasis is present in 35% of patients with apparent localized disease; lymph node involvement outside the cavity of origin is considered disseminated disease. Hematogenous spread is usually to the bone marrow, bone, liver and/or skin.

Skeletal muscle metastasis in patients with neuroblastoma is rare.


Faingold R, Babyn P, Yoo SJ, et al. Neuroblastoma with atypical metastases to cardiac and skeletal muscles: MRI features. Pediatric Radiology (2003) 33: 584-586.

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare