Heather Borders, MD
about 1 year ago
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Joseph Junewick, MD FACR
|Diagnostic Category: Neoplasia Malignant
|Created: about 1 year ago
|Updated: about 1 year ago
Teenager with intermittent headache.
MR – T1 hypointense and T2, FLAIR and post-gadolinium hyperintense lesion of the right anterior column of the fornix.
The fornix is a component of the limbic system and largely responsible for memory formation and consolidation. It arises from fibers of the alveus of the hippocampus to form a white matter tract coursing along the anterior thalamus (anterior columns), the inferior aspect of the septa pellucida (crura and body), posterior thalmus and anterior commissure (posterior columns) and into the mammillary bodies, forming the Papez circuit. The fornix may be affected by infection (limbic encephalitis – Herpes), inflammation/demeylination (multiple sclerosis), metabolic disease (Wernicke encephalopathy), trauma/ischemia and neoplasia. Tumors that may involve the fornix include glioblastoma multiforme, astrocytomas (especially fibrillary pilocytic astrocytomas in children), and lymphoma.
Thomas AG, Koumellis P, Dineen RA. The Fornix in Health and Disease: An Imaging Review.RadioGraphics (2011); 31: 1107-1121.