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Hepatoblastoma - Li Fraumini Syndrome
Joseph Junewick, MD FACR
over 2 years ago
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ARSt Case Repository

Forniceal Astrocytoma

Case Detail

Anatomy: Brain-Spine
Junewick
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 2 years ago
Updated: over 2 years ago
Tags: PEDS
Modality/Study Types: MR
Activities:
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History

Teenager with intermittent headache.


Case Images


Diagnosis

Forniceal Astrocytoma

Findings

MR – T1 hypointense and T2, FLAIR and post-gadolinium hyperintense lesion of the right anterior column of the fornix.

Discussion

The fornix is a component of the limbic system and largely responsible for memory formation and consolidation. It arises from fibers of the alveus of the hippocampus to form a white matter tract coursing along the anterior thalamus (anterior columns), the inferior aspect of the septa pellucida (crura and body), posterior thalmus and anterior commissure (posterior columns) and into the mammillary bodies, forming the Papez circuit. The fornix may be affected by infection (limbic encephalitis – Herpes), inflammation/demeylination (multiple sclerosis), metabolic disease (Wernicke encephalopathy), trauma/ischemia and neoplasia. Tumors that may involve the fornix include glioblastoma multiforme, astrocytomas (especially fibrillary pilocytic astrocytomas in children), and lymphoma.

Reference

Thomas AG, Koumellis P, Dineen RA. The Fornix in Health and Disease: An Imaging Review.RadioGraphics (2011); 31: 1107-1121.



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