Schizencephaly and Septo optic dysplasia
Heather Borders, MD
over 7 years ago
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Relapsed Leukemia - Testicle
Joseph Junewick, MD FACR
|Diagnostic Category: Neoplasia Malignant
|Created: over 5 years ago
|Updated: over 5 years ago
9 year old with history of leukemia and asymmetric testicular size.
Relapsed Leukemia – Testicle
US – Enlarged hypoechoic right testicle with hyperemia (right testicular calculated volume twice that of the left).
Leukemic infiltration to the testis has been found at autopsy in 40%–65% of patients with acute leukemia and in 20%–35% of patients with chronic leukemia. Testicular involvement with acute lymphoblastic leukemia is reported in 5%–10% of patients, with the majority found during clinical remission. A blood-testis barrier limiting the effect of chemotherapeutic agents in the testes explains the persistence of leukemia in the testes after remission. Any patient with a testicular mass found during the course of leukemia should undergo cytologic or histologic evaluation, because chemotherapy does not completely eliminate tumor cells from the testes. The US appearance is similar to that of lymphoma.
Dogra VS, Gottlieb RH, Oka M,et al. Sonography of the Scrotum. Radiology (2003); 227:18-36.