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Hirschprung Disease
Joseph Junewick, MD FACR
over 9 years ago
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Prenatal Germinal Matrix Hemorrhage

Case Detail

Anatomy: Brain-Spine
Joseph Junewick, MD FACR
Diagnostic Category: Vascular
Created: over 9 years ago
Updated: over 9 years ago
Tags: PEDS
Modality/Study Types: MR
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“Intraventricular” mass on prenatal ultrasound.

Case Images


Prenatal Germinal Matrix Hemorrhage


Prenatal MR – Mixed signal lesion at the caudothalamic groove protruding into the lateral ventricle.


Hemorrhage usually appears as a hypointense area on T2-weighted images. Intraventricular hemorrhage can appear as debris layering in the dependent portion of the ventricle or as a focal hematoma. The detection of small subependymal hemorrhages is more difficult, partly because the normal germinal matrix has similar signal intensity to blood (hypointense on T2-weighted images and hyperintense on T1-weighted images) because of its high cellularity. Gradient-echo sequences may be useful to help to confirm the presence of blood, because the hemorrhage appears more hypointense than the germinal matrix. Differential diagnosis of signal disturbance at the caudothalamic groove includes infection and tuberous sclerosis.


Glenna OA, Barkovich AJ. Magnetic Resonance Imaging of the Fetal Brain and Spine: An Increasingly Important Tool in Prenatal Diagnosis, Part 1. Neuroradiology (2006); 27:1604-1611.

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