Hosting 718 files, 2916 images, and 4 contributors.

 
Random Case

Ectopic posterior pituitary
Heather Borders, MD
over 6 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Osteogenesis Imperfecta

Case Detail

Anatomy: Musculoskeletal
Junewick
Joseph Junewick, MD FACR
Diagnostic Category: Developmental or Congenital
Created: over 6 years ago
Updated: over 6 years ago
Tags: PEDS
Modality/Study Types: CR
Activities:
Adobe32 PDF Imagej32 ImageJA

History

2 week old who fell from bed.


Case Images


Diagnosis

Osteogenesis Imperfecta

Findings

CR – Skull: Macrocephaly, osteopenia and wormian bones. Right Femur: Osteopenia, marked varus bowing with foreshortening, and healing fracture. Right Leg: Osteopenia, acute transverse fractures of the tibia and fibula, flared distal tibial metaphysis.

Discussion

Osteogenesis imperfecta represents a clinically, radiographically and genetically diverse group of disorders of decreased bone density related to quantitative and/or structural deficits of type I collagen. Morbidity is largely due to fractures with subsequent deformity. Radiographic features include: generalized osteoporosis, retarded calvarial bone formation with wormian bones, collapsed vertebrae, rib fractures in severe cases, acetabular protrusio, and tubular bones with thin cortices (fractures, bowing and compression). Radiographic phenotypes are classified using the Sillence system; this has prognostic implications but does not imply underlying pathology.

Reference

Spranger JW, Brill PW, Poznanski AK. Bone dysplasias: An atlas of genetic disorders of skeletal development, 2nd Ed. Oxford University Press (2002).



Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare