In Utero/Congenital HSV
Heather Borders, MD
over 5 years ago
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Highly primitive malignant neoplasm of the Pancreas
Joseph Junewick, MD FACR
|Diagnostic Category: Neoplasia Malignant
|Created: over 8 years ago
|Updated: over 7 years ago
4 year old male with elevated estrogen levels and gynecomastia.
Highly primitive malignant neoplasm of the pancreas with features of juvenile granulosa cell tumor.
Immunoperoxidase positivity for inhibin, CD10, calretin, estrogen receptors and progesterone receptors.
US – Hyperemic solid and cystic left upper quandrant mass.
CT – Well-circumscribed mass arising from the tail of the pancreas.
Granulosa/theca cell tumors generally involve the gonads. These tumors are large at the time of diagnosis and usually solid but occasionally contain cystic components. Most granulosa/theca cell tumors produce estrogen, resulting in precocious development in females and gynecomastia in males.