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Joseph Junewick, MD FACR
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Juvenile Granulosa Cell Tumor of the Testicle

Case Detail

Anatomy: Genitourinary
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 7 years ago
Updated: over 7 years ago
Tags: PEDS
Modality/Study Types: US
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Newborn with left scrotal mass.

Case Images


Juvenile Granulosa Cell Tumor of the Testicle

Clinical Notes

Alpha fetoprotein – 25707 ng/mL


US – Testicular tissue is replaced by cystic mass with thick hyperemic septae. Hydrocele is present.

Pathology – Bivalved specimen showing a yellowish multicystic mass with thick septae and no recognizable testicular tissue.


Granulosa cell tumor is a sex-cord stromal neoplasm with two subtypes – adult and juvenile. Juvenile granulosa cell tumor is a very rare testicular lesion usually diagnosed during infancy by the presence of a scrotal mass. In 20% of cases, anomalies of the Y chromosome and/or ambiguous genitalia are present. Imaging reveals a well-defined, large multicystic intratesticular mass. Differential diagnosis includes germ cell neoplasm and testicular torsion. Orchiectomy is the only treatment necessary.


Gun F, Erginel B, Kilicaslan I, et al. A rare neonatal testicular tumor: juvenile granulosa cell tumor of the infant: a report of 3 cases. J Pediatr Hematol Oncol 2010; 32(4): e158-e159.


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