Hosting 728 files, 2951 images, and 4 contributors.

Random Case

Lens dislocation
Joseph Junewick, MD FACR
over 11 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Devic's Disease

Case Detail

Anatomy: Neck-Face
Joseph Junewick, MD FACR
Diagnostic Category: Infectious-Inflammatory
Created: over 10 years ago
Updated: over 10 years ago
Tags: PEDS
Modality/Study Types: MR
Adobe32 PDF Imagej32 ImageJA


8 year old female with acute onset of blindness.

Case Images


Devic’s Disease

Clinical Notes

CSF – Pleocytosis but no oligoclonal bands.


MR – FS postgadolinium T1 images show hyperintensity in the optic chiasm and the prechiasmatic right optic nerve.


Devic’s disease (neuromyelitis optica) is a demyelinating disease distinct from multiple sclerosis characterized by acute onset of visual loss and paresthesias. Devics’s disease is often preceded by a viral-like prodrome of headache, fatigue, myalgias, respiratory symptoms and gastrointestinal distress. There is a female prepoderance; more than half experience relapse. CSF analysis shows pleocytosis and absence of oligoclonal bands. MR demonstrates edema and inflammation in the optic pathways often with no other evidence of central demyelination. Evaluation of the spinal cord usually shows long segment (>3 vertebral levels) central edema.


VandeVyver V, Limmerling M, DePotter R, Verstaete K. Devic’s Neuromyelitis optica: Clinical and Imaging Findings. JBR-BTR (2007); 90:284-287.

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare