Hosting 718 files, 2916 images, and 4 contributors.

 
Random Case

Angiofibroma
Joseph Junewick, MD FACR
over 7 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Coagulopathy of the Newborn

Case Detail

Anatomy: Brain-Spine
Junewick
Joseph Junewick, MD FACR
Diagnostic Category: Vascular
Created: over 6 years ago
Updated: over 6 years ago
Tags: PEDS
Modality/Study Types: CT
Activities:
Adobe32 PDF Imagej32 ImageJA

History

1 day old with lethargy.


Case Images


Diagnosis

Coagulopathy of the Newborn,

Clinical Notes

Precipitous at home delivery. Vitamin K not administered.

Findings

CT – Large posterior fossa hematoma (hemispheric and extra-axial) with fluid-fluid level and obstructive hydrocephalus.

Discussion

Neonatal bleeding results from disorders of platelets, coagulation proteins, and vascular integrity. While healthy newborns have low levels of some coagulation proteins, this is normally balanced by the paralleled decrease in fibrinolytic activity. Causes of neonatal bleeding may include platelet disorders (thrombocytopenia from syndromes, infection, consumption and hemolytic disease and abnormal platelet function from vonWillebrand disease and indomethicin therapy), deficient coagulation proteins (Hemophilia A, Hemophilia B, Factor V VII X XI or XII deficiency, afibrogenemia, and vitamin K deficiency), combined platelet and coagulation protein defects (disseminated intravascular coagulation, hepatic dysfunction), and abnormal sequestration (hemangiomas).

Reference

Hanigan WC, Powell FC, Palagallo G, Miller TC. Lobar Hemorrhages in fullterm neonates. Child Nerv Sys (1995); 11(5):276-280.



Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare