Hosting 728 files, 2951 images, and 4 contributors.

Random Case

Subtrochanteric Stress Fracture
Joseph Junewick, MD FACR
over 9 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Leptomeningeal PNET

Case Detail

Anatomy: Brain-Spine
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 10 years ago
Updated: over 10 years ago
Tags: PEDS
Modality/Study Types: MR
Adobe32 PDF Imagej32 ImageJA


10 year old male with seizure.

Case Images


Leptomeningeal PNET


MR – Diffuse nodular leptomeningeal enhancement; no parenchymal lesion.


Extracerebellar PNETs are uncommon central nervous system tumors affecting children and young adults. Typically these tumors are found in the supratentorial parenchyma and rarely the spinal cord with only a few cases reported to involve the leptomeninges.

PNETs arising outside of the central nervous system most frequently involve the deep soft tissues of the trunk and lower extremities. While morphologically similar to CNS PNETs, these tumors are immunohistochemically and cytogenetically distinct exhibiting high amounts of the MIC2 antigen (CD99) and translocation of chromosomes 11 and 22 (q24;q12).

PNET of the dura represents a form of peripheral PNET. Dural PNET may be focal or diffuse. Overall, peripheral type PNETs have better prognosis than CNS PNETs, especially if they are completely resected.


Dedeurwaerdere F, Giannini C, Sciot R, Rubin BP, et al. Primary peripheral PNET/Ewing’s Sarcoma of the dura: a clinicopathological entity distinct from central PNET. Mod Pathol 2002; 15(6):673-678.

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare