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Joseph Junewick, MD FACR
over 5 years ago
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ARSt Case Repository

Choroid Plexus Carcinoma

Case Detail

Anatomy: Brain-Spine
Junewick
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 7 years ago
Updated: over 7 years ago
Tags: PEDS
Modality/Study Types: MR
Activities:
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History

3 year old male with left-sided weakness.


Case Images


Diagnosis

Choroid Plexus Carcinoma

Findings

MR – Axial sagittal images show a macrolobulated T2 isointense and postgadolinium hyperintense mass originating from the atrium of the right lateral ventricle and invading the right cerebrum. Note the marked vasogenic edema, mass effect and large intralesional flow voids.

Discussion

Choroid plexus carcinoma most often occur in children between the ages of 2 and 4 years. Choroid plexus carcinomas account for 30-40% of choroid tumors in children. Patients may present with focal neurologic deficits, seizure or hydrocephalus.

Choroid plexus carcinomas almost always grow into the brain through the ventricular wall and cause vasogenic edema. Intralesional cyst and hemorrhage are common. Choroid plexus carcinoma can be difficult to differentiate from aggressive choroid plexus papillomas. Both choroid plexus carcinomas and aggressive papilloma commonly metastasize by CSF pathways.

Other tumors involving the choroid plexus are unusual and include meningioma, lymphoma, metastatic disease (neuroblastoma, retinoblastoma, Wilms, and melanoma), myofibromas and xanthogranulomas.

Reference

Naeni RM, Yoo JH, Hunter JV. Spectrum of choroid plexus lesions in children. AJR 2009; 192:32-41.



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