Heather Borders, MD
over 4 years ago
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Focal nodular hyperplasia
Joseph Junewick, MD FACR
|Diagnostic Category: Vascular
|Created: over 6 years ago
|Updated: over 5 years ago
5 year old female with history of autologous bone marrow transplantation for metastatic neuroblastoma.
Focal nodular hyperplasia.
Image from surveillance CT, 6 months after initiation of retinoic acid therapy.
Multiple small round enhancing hepatic lesions.
The etiology of focal nodular hyperplasia is obscure but likely related to localized vascular anomaly or circulatory disturbance. FNH has been reported in children treated for solid tumors. This may be related to alkylating agents, veno-occlusive disease or radiation therapy; retinoic acid can produce both coagulopathy and thrombotic events.