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Clavicle Fracture
Joseph Junewick, MD FACR
over 5 years ago
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Focal nodular hyperplasia

Case Detail

Anatomy: Gastrointestinal
Junewick
Joseph Junewick, MD FACR
Diagnostic Category: Vascular
Created: over 5 years ago
Updated: over 4 years ago
Tags: PEDS
Modality/Study Types: CT
Activities:
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History

5 year old female with history of autologous bone marrow transplantation for metastatic neuroblastoma.


Case Images


Diagnosis

Focal nodular hyperplasia.

Clinical Notes

Image from surveillance CT, 6 months after initiation of retinoic acid therapy.

Findings

Multiple small round enhancing hepatic lesions.

Discussion

The etiology of focal nodular hyperplasia is obscure but likely related to localized vascular anomaly or circulatory disturbance. FNH has been reported in children treated for solid tumors. This may be related to alkylating agents, veno-occlusive disease or radiation therapy; retinoic acid can produce both coagulopathy and thrombotic events.



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