Focal nodular hyperplasia
Case Detail
| Anatomy: Gastrointestinal |
Joseph Junewick, MD FACR |
| Diagnostic Category: Vascular |
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| Created: over 4 years ago |
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| Updated: over 3 years ago |
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| Tags:
PEDS
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| Modality/Study Types:
CT
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Activities: PDF ImageJA |
History
5 year old female with history of autologous bone marrow transplantation for metastatic neuroblastoma.
Case Images
Diagnosis
Focal nodular hyperplasia.
Clinical Notes
Image from surveillance CT, 6 months after initiation of retinoic acid therapy.
Findings
Multiple small round enhancing hepatic lesions.
Discussion
The etiology of focal nodular hyperplasia is obscure but likely related to localized vascular anomaly or circulatory disturbance. FNH has been reported in children treated for solid tumors. This may be related to alkylating agents, veno-occlusive disease or radiation therapy; retinoic acid can produce both coagulopathy and thrombotic events.



