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Joseph Junewick, MD FACR
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Melanotic neuroectodermal tumor of infancy

Case Detail

Anatomy: Genitourinary
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Benign
Created: over 11 years ago
Updated: over 11 years ago
Tags: PEDS
Modality/Study Types: US
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Nearly 5 month old male with scrotal mass.

Case Images


Epididymal melanotic neuroectodermal tumor of infancy

Clinical Notes

Elevated vanillylmandelic acid (VMA).


US – Hydrocele with hypervascular mass adjacent to the normal testicle.

Gross Pathology – The tumor originates from the epididymus. The cut surface of the tumor is white and fibrous with a punctate central dark spot.


Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor. More than 90% involve the head and heck (most often the maxilla) but skin, mediastinum, long bones, uterus, ovary and epididymus have been reported. MNTI are almost always solitary with an average age of onset between 1 and 6 months. While MNTI grow very rapidly, the clinical course is benign with only 15% incidence of local recurrence.


Lee SB et al. Melanotic Neuroectodermal Tumor of Infancy in the Epididymus: A Case Report. Kor J Ped (2004); 47(12):1334-7.

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