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Tuberous Sclerosis - Newborn
Joseph Junewick, MD FACR
over 7 years ago
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ARSt Case Repository

Renal Cell Carcinoma

Case Detail

Anatomy: Genitourinary
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 11 years ago
Updated: over 10 years ago
Tags: PEDS
Modality/Study Types: US CT
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7 year old female with remote history of neuroblastoma presenting for surveillance CT.

Case Images


Renal cell carcinoma

Clinical Notes

Ultrasound was performed after CT.


CT- peripheral, round, ill-defined, hypodense right renal lesion.

US – round hyperechoic (solid) lesion.


Second malignancies occur in 13-25% of children, usually 15 -19 years after treatment of the primary malignancy. Most second malignancies are sarcomas, leukemia or lymphoma. The etiology may be related to genetic cancer predisposition or therapy. Second malignancies with neuroblastoma is more common when the diagnosis of neuroblastoma is made before 1 year of age but is also associated with radiation therapy and the use of alkylating agents.


Donnelly LF, et al. Renal cell carcinoma after therapy of neuroblastoma. AJR 1996; 167:915-917.

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