Hosting 728 files, 2951 images, and 4 contributors.

Random Case

Heather Borders, MD
over 10 years ago
Enter A Workflow
Standard2   Academic2

Please choose a workflow. A standard workflow allows you to browse the repository with full case detail; the academic workflow allows you to browse the repository with limited case detail revealed. Double click on the images to launch image viewer.

ARSt Case Repository

Neurofibromatosis with pathologic fracture

Case Detail

Anatomy: Musculoskeletal
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Benign
Created: over 10 years ago
Updated: over 10 years ago
Tags: PEDS
Modality/Study Types: CR
Adobe32 PDF Imagej32 ImageJA


9 year old female with neurofibromatosis.

Case Images


Neurofibromatosis with pathologic fracture


CR – Lateral view of the leg demonstrates multilocular cystic lucency with segmental sclerosis in the anterior proximal tibial diaphysis with associated apex anterior tibial bowing. Note the transverse fracture through the anterior aspect of the tibia.


The cystic lucencies in this case likely represent a combination of non-ossifying fibroma, fibrocortical defects and mesodermal dysplasia. Osseous dysplasia weakens the bone and consequently predisposes to fracture. Nonunion and pseudoarthrosis occur in as many as 13% of these pathologic fractures.


Ozonoff M. Pediatric Orthopedic Radiology, 2nd Ed. WB Suanders (1992).

Corporate Office: 616.363.7272, 3264 North Evergreen Drive, Grand Rapids, MI 49525

Spectrum Health Helen Devos Childrens Hospital GE HealthCare