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Schwachman Syndrome
Joseph Junewick, MD FACR
over 7 years ago
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Ganglioglioma

Case Detail

Anatomy: Brain-Spine
Junewick
Joseph Junewick, MD FACR
Diagnostic Category: Neoplasia Malignant
Created: over 7 years ago
Updated: over 7 years ago
Tags: PEDS
Modality/Study Types: MR
Activities:
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History

13 year old male with persistent headache.


Case Images


Diagnosis

Ganglioglioma

Findings

MR – Axial and coronal T2 and postgadolinium FSPGR images show a solid and cystic enhancing left temporal lobe mass.

Discussion

Ganglioglioma is a slow growing low grade neoplasm. Approximately 80% occur in children and young adults, with a peak between 10 and 20 years. The temporal lobe is the most common location and often associated with seizure.

Gangliogliomas may be different in children compared to adults. Lesions are up to 8 times larger in children; this may be related to higher mitotic indices, more compliant skull (patent sutures), or location. Cystic change is more common in children.

Lesions are typically iso- to hyperintense on T1, hyperintense on T2 and show variable enhancement. Calcifications are present in 35%.

Reference

Provenzale JM, et al. Comparison of patient age with MR imaging features of gangliogliomas. AJR (2000); 174:859-862.

Koeller KK and Henry JM. Superficial gliomas: Radiologic-Pathologic correlation. Radiographics (2001); 21(6):1533.



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